The Golob Lab

Understanding how the host and microbiome interact in both health and disease.


Jonathan Golob, MD PhD

Assistant Professor

University of Michigan


Jonathan Golob is an assistant professor of Infectious Disease at the University of Michgan. His research interests include how the host and microbiome interact in health and disease. He has a particular focus on the immunocompromised host. He also contributes to computational biology tool development, and is a proponent of reproducible science via workflows and containerized software.


  • Microbiome Science
  • Infectious Disease
  • Immunocompromised Hosts


  • Infectious Disease Fellowship, 2017

    University of Washington

  • Internal Medicine Residency, 2013

    University of Washington

  • Medical Degree, 2011

    University of Washington

  • PhD in Pathology, 2009

    University of Washington

  • BSc in Biomedical Engineer and Computer Science, 2001

    Johns Hopkins University

Software Projects


AWS Batch Task Watcher


Automated rRNA Filtering


A gene and allele oriented WGS analysis workflow


Maximum Likelihood 16S Amplicon Pipeline

Recent & Upcoming Talks

Butyrogenic Bacteria after Acute Graft Versus Host Disease Associate with the Development of Steroid Refractory GVHD

Background : Steroid refractory acute graft-versus-host-disease (GVHD) after hematopoietic cell transplantation (HCT) is highly morbid …

Recent Publications

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HIV DNA levels and decay in a cohort of 111 long-term virally suppressed patients

BACKGROUND AND METHOD: We examined specimens from 111 HIV-infected participants virally suppressed on ART for a minimum of 5 years who …

Functional Analysis of Metagenomes by Likelihood Inference (FAMLI) Successfully Compensates for Multi-Mapping Short Reads from Metagenomic Samples

Short-read metagenomics use high-throughput sequencing to reveal the functional capability of microbial communities. The computational …